Vaccination Strategies in Preterm Infants

Vaccinating preterm infants poses unique challenges due to their immature immune systems and often complicated clinical courses. However, timely immunization remains crucial to protect these vulnerable infants from life-threatening infections. This session provides guidance on current recommendations for vaccinating preterm and low-birth-weight infants, including schedules, timing, and catch-up protocols aligned with WHO and national guidelines. Participants will learn how to address concerns related to vaccine efficacy, adverse reactions, and contraindications in NICU environments. Emphasis is placed on vaccines for diseases such as hepatitis B, pertussis, influenza, and rotavirus, which carry increased risks for preterm populations. Evidence from recent studies supports that immunogenicity in preterm infants is generally sufficient and side effects are minimal, reinforcing the need to maintain standard schedules. Strategies for improving vaccine uptake in NICUs and educating caregivers about the safety and necessity of timely immunization will also be discussed, promoting comprehensive protection during this critical stage of development.

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